By mikkygoomes at 2020-09-02 • 0 collector • 117 pageviews

Joint pain is an extremely common health condition that affects more than 22% of the population of the United States, which amounts to over 54 million people. The biological mechanism through which white willow bark inhibits joint pain is unique and interesting- when ingested, the salicin in white willow bark extract blocks extracellular signalling pathways and prevents the inflammation of new blood vessels in the joint regions, modulating inflammatory action and pain1. A clinical trial performed in 2014 found that devil's root extract is able to induce the migration of leukocytes, or white blood cells, to the location of joint pain, and minimize the overall inflammation and pain caused by joint damage4.

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